Therapeutic Specialties Archives

Publication

Under-reporting of Venous and Arterial Thrombotic Events in Randomized Clinical Trials: A Meta-analysis

For the detection of unwanted outcomes of new interventions, physicians rely on adverse event reporting.…

webdev2010 年 3 月 1 日

Publication

Detection of Lymph Node Metastases by Gadolinium-enhanced Magnetic Resonance Imaging: Systematic Review and Meta-analysis

Gadolinium-based contrast agents are used with magnetic resonance imaging (MRI) to highlight tumor vascularity in…

webdev2010 年 2 月 24 日

Publication

The Use of Biosimulation in the Design of a Novel Multilevel Weight Loss Maintenance Program for Overweight Children

Weight loss outcomes achieved through conventional behavior change interventions are prone to deterioration over time.…

webdev2010 年 2 月 18 日

Publication

Population Pharmacokinetics of Teduglutide Following Repeated Subcutaneous Administrations in Healthy Participants and in Patients with Short Bowel Syndrome and Crohn’s Disease

Teduglutide is a GLP-2 analog currently evaluated for the treatment of short bowel syndrome, Crohn's…

webdev2010 年 1 月 1 日

Publication

Clinical Trial Simulations in Pediatric Patients Using Realistic Covariates: Application to Teduglutide, a Glucagon-like Peptide-2 Analog in Neonates and Infants with Short-bowel Syndrome

Teduglutide, a synthetic glucagon-like peptide-2 (GLP-2) analog with activity relating to the regeneration, maintenance, and…

webdev2009 年 12 月 1 日

Publication

In Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen Extract

Mangosteen is a xanthone-containing fruit found in Southeast Asia for which health claims include maintaining healthy immune…

webdev2009 年 9 月 1 日

Publication

Model-based Prediction of Phase 3 Overall Survival in Colorectal Cancer on the Basis of Phase 2 Tumor Dynamics

We developed a drug-disease simulation model to predict antitumor response and overall survival in phase…

webdev2009 年 9 月 1 日

Publication

Excluding Venous Thromboembolism Using Point of Care D-dimer Tests in Outpatients: A Diagnostic Meta-analysis

This article is a review the evidence on the diagnostic accuracy of the currently available…

webdev2009 年 8 月 14 日

Publication

On the Use of Change in Tumor Size to Predict Survival in Clinical Oncology Studies: Toward a New Paradigm to Design and Evaluate Phase 2 Studies

Drug-independent models that link biomarker response to clinical end points are critical to support early…

webdev2009 年 8 月 1 日

Publication

Pharmacokinetic Analysis of Capsaicin After Topical Administration of a High-concentration Capsaicin Patch to Patients With Peripheral Neuropathic Pain

Capsaicin, a pungent compound in chili peppers, is a highly selective agonist for the transient…

webdev2009 年 8 月 1 日

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Under-reporting of Venous and Arterial Thrombotic Events in Randomized Clinical Trials: A Meta-analysis

Detection of Lymph Node Metastases by Gadolinium-enhanced Magnetic Resonance Imaging: Systematic Review and Meta-analysis

The Use of Biosimulation in the Design of a Novel Multilevel Weight Loss Maintenance Program for Overweight Children

Population Pharmacokinetics of Teduglutide Following Repeated Subcutaneous Administrations in Healthy Participants and in Patients with Short Bowel Syndrome and Crohn’s Disease

Clinical Trial Simulations in Pediatric Patients Using Realistic Covariates: Application to Teduglutide, a Glucagon-like Peptide-2 Analog in Neonates and Infants with Short-bowel Syndrome

In Vitro Inhibition of Multiple Cytochrome P450 Isoforms by Xanthone Derivatives from Mangosteen Extract

Model-based Prediction of Phase 3 Overall Survival in Colorectal Cancer on the Basis of Phase 2 Tumor Dynamics

Excluding Venous Thromboembolism Using Point of Care D-dimer Tests in Outpatients: A Diagnostic Meta-analysis

On the Use of Change in Tumor Size to Predict Survival in Clinical Oncology Studies: Toward a New Paradigm to Design and Evaluate Phase 2 Studies

Pharmacokinetic Analysis of Capsaicin After Topical Administration of a High-concentration Capsaicin Patch to Patients With Peripheral Neuropathic Pain

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