How PBPK Modeling Can Replace Drug-Drug Interaction Studies
Patients often take more than one drug at a time, especially elderly patients and those…
Jim Gallagher2020 年 11 月 12 日
Galderma Achieves FDA Approval of AKLIEF® (trifarotene)
In October 2019, Galderma announced that the U.S. FDA approved AKLIEF® (trifarotene) Cream, 0.005% for the…
Certara2020 年 11 月 9 日
PBPK modeling supports approval of breakthrough cancer drug
Pharmacyclics’ (now AbbVie) Imbruvica (ibrutinib) is an anticancer drug targeting B-cell malignancies. Leveraging the US…
Certara2020 年 10 月 23 日
Model-Informed Precision Dosing: Background, Requirements, Validation, Implementation, and Forward Trajectory of Individualizing Drug Therapy
Model-informed precision dosing (MIPD) has become synonymous with modern approaches for individualizing drug therapy, in…
Jieun Choe2020 年 10 月 12 日
Intro to Smart In Silico Tools to Aid in Translating In Vitro & In Vivo Studies
Safety issues account for about a quarter of the attrition in drug projects, and can…
Jim Gallagher2020 年 10 月 5 日
