Enhancing Pharmacokinetics Workflows at Charles River
PreclinicalPhoenix™ Integral Data Repository Charles River, a global leader in drug development, sought to improve…
Danielle Pillsbury2024 年 11 月 13 日
PBPK Modeling to Support Bioequivalence & Generic Product Approvals
Physiologically-based pharmacokinetic modeling can be used to support bioequivalence (BE) assessment of complex and locally…
Jim Gallagher2024 年 11 月 12 日
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody
The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…
Danielle Pillsbury2024 年 11 月 4 日
On-ramps to popPK: Building Better Models with GUI, Code, or Both
A critical component of popPK studies is popPK modeling, where mathematical models are developed to…
Danielle Pillsbury2024 年 10 月 18 日
Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system qualification of the Simcyp Simulator
The article "Prediction of CYP-mediated DDIs involving inhibition: Approaches to address the requirements for system…
Danielle Pillsbury2024 年 8 月 26 日
Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL) to Nonalcoholic Steatohepatitis (NASH)
The article “Considerations for Physiologically Based Modeling in Liver Disease: From Nonalcoholic Fatty Liver (NAFL)…
Danielle Pillsbury2024 年 8 月 26 日
A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator
This collaborative effort by Certara and the Centre for Applied Pharmacokinetic Research (CAPKR) at The…
Danielle Pillsbury2024 年 7 月 24 日
Hosted Phoenix for High Performance PK/PD
如何最大限度地提高 PK/PD 分析和定量药理学模型的效率？Well-trained scientists, reproducible workflows,…
Danielle Pillsbury2024 年 7 月 8 日
