Modeling and Simulation - PK/PD Archives | 第 33 页，共 37 页

知识库

Why Should You Evaluate Dose Proportionality?

Dose proportionality is a common phrase used pharmacokinetics. Early in the pre-clinical development process, we…

Nathan Teuscher2011 年 2 月 17 日

知识库

What is the Difference Between PK and TK?

Explore the key differences between pharmacokinetics (PK) and toxicokinetics (TK), their roles in drug development,…

Nathan Teuscher2011 年 2 月 15 日

知识库

Why are PK Parameters Lognormally Distributed?

The statistical analysis of pharmacokinetic parameters is often overlooked and not always well understood. The…

Nathan Teuscher2011 年 2 月 10 日

知识库

What are Direct and Indirect Pharmacodynamic Models?

When constructing pharmacodynamic (PD) models, you will often encounter the adjectives “direct” and “indirect” describing…

Nathan Teuscher2011 年 2 月 8 日

知识库

What is Modeling and Simulation?

I am currently attending a short conference on modeling and simulation in pediatric clinical pharmacology,…

Nathan Teuscher2011 年 2 月 1 日

Publication

Immediate Consequences of Cigarette Smoking: Rapid Formation of Polycyclic Aromatic Hydrocarbon Diol Epoxides

Polycyclic aromatic hydrocarbons (PAH) are among the likely major causative agents for lung cancer in…

webdev2011 年 2 月 1 日

Knowledge Base

Relationship Between AUC and Volume of Distribution

A few days ago on the pharmacokinetics listserve PharmPK, the following question appeared: I’m having…

Nathan Teuscher2011 年 1 月 26 日

知识库

Where Did the 80-125% Bioequivalence Criteria Come From?

Most people involved in clinical pharmacokinetics are familiar with the 80-125% criterion. This criterion is…

Nathan Teuscher2011 年 1 月 24 日

Knowledge Base

Generics and Bioequivalence

As the debate about health care in the United States continues forward, the term “generic…

Nathan Teuscher2011 年 1 月 10 日

知识库

What are Compartmental Models?

Learn about compartmental models and their importance in pharmacokinetics. Find out how they simplify drug…

Nathan Teuscher2011 年 1 月 5 日

Modeling and Simulation – PK/PD