Modeling and Simulation - PK/PD Archives | 第 32 页，共 37 页

Publication

Clinical Tolerance and Toxicity of Intravenous Baclofen: A Pilot Study in a Canine Model

Assess safety and tolerance of intravenous (IV) baclofen using a dog model. Prospective pharmacokinetic study…

webdev2011 年 7 月 1 日

Publication

Model-based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor

A model-based strategy was used to inform the early clinical development of anacetrapib, a novel…

webdev2011 年 6 月 1 日

Publication

Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-experienced and CCR5 Antagonist-naive Patients

TBR-652 is a novel CCR5 antagonist with potent in vitro anti-HIV activity. The objective of…

webdev2011 年 4 月 12 日

知识库

What to Do with Those BLQs!

BLQ values are like those pimples we used to get as teenagers. They…

Nathan Teuscher2011 年 4 月 6 日

Knowledge Base

The Difference Between Vd and Vss

There are many terms used to represent volume of distribution, but two common ones are…

Nathan Teuscher2011 年 3 月 31 日

知识库

What is Shrinkage?

In 2007, Mats Karlsson and Radojka Savic published a perspective in Clinical Pharmacology & Therapeutics…

Nathan Teuscher2011 年 3 月 29 日

知识库

Is a Monte Carlo Simulation an Exotic Drink?

The term “Monte Carlo simulation” is often used in the modeling and simulation literature with…

Nathan Teuscher2011 年 3 月 21 日

知识库

What is WinNonlin?

A reader suggested that I write a similar post about WinNonlin. Great idea! Thank you!…

Nathan Teuscher2011 年 3 月 16 日

知识库

个体 PK 和群体 PK 有什么区别？

药代动力学分析通常分为两个领域...... "PK "和 "群体 PK"。Sometimes the…

Nathan Teuscher2011 年 3 月 14 日

知识库

Blood or Plasma? Which Should You Assay for Drug Concentration?

Explore blood vs. plasma drug concentration assays. Learn their differences, relationships, and impact on accurate…

Nathan Teuscher2011 年 2 月 19 日

Modeling and Simulation – PK/PD

Clinical Tolerance and Toxicity of Intravenous Baclofen: A Pilot Study in a Canine Model

Model-based Development of Anacetrapib, a Novel Cholesteryl Ester Transfer Protein Inhibitor

Pharmacokinetics and Pharmacodynamics of TBR-652, a Novel CCR5 Antagonist, in HIV-1-Infected, Antiretroviral Treatment-experienced and CCR5 Antagonist-naive Patients

What to Do with Those BLQs!

The Difference Between Vd and Vss

What is Shrinkage?

Is a Monte Carlo Simulation an Exotic Drink?

What is WinNonlin?

个体 PK 和群体 PK 有什么区别？

Blood or Plasma? Which Should You Assay for Drug Concentration?

订阅时事通讯

快捷链接

解决方案

联系我们