Drug Asset Evaluation: Increasing “Probability of Success” of a Deal
Certara’s due diligence/asset evaluation teams are comprised of drug development and commercialization experts who advise…
webdev2017 年 8 月 24 日
Abundance of Hepatic Transporters in Caucasians: A Meta-analysis
The aim of this study was to derive quantitative abundance values for key hepatic transporters…
webdev2016 年 10 月 1 日
Model-based Meta-analysis: An Innovative Methodology Comes of Age
MBMA integrates internal and external drug development data to inform proprietary commercial and R&D decisions.…
webdev2016 年 7 月 14 日
Short-term Efficacy Reliably Predicts Long-term Clinical Benefit in Rheumatoid Arthritis Clinical Trials as Demonstrated by Model-based Meta-analysis
The objective of this study was to assess the relationship between short-term and long-term treatment…
webdev2016 年 7 月 1 日
Does Age Affect Gastric Emptying Time? A Model-based Meta-analysis
Gastric emptying (GE) is often reported to be slower and more irregular in premature neonates than…
webdev2015 年 5 月 1 日
A Model-based Dose-response Meta-analysis of Ocular Hypotensive Agents as a Drug Development Tool to Evaluate New Therapies in Glaucoma
PURPOSE: To characterize dose and response for intraocular pressure (IOP) reduction and incidence of hyperemia…
webdev2015 年 5 月 1 日
Time Course of Bone Mineral Density Changes with Denosumab Compared with Other Drugs in Postmenopausal Osteoporosis: A Dose-response-based Meta-analysis
Our objective was to compare the time course of bone mineral density (BMD) changes at…
webdev2014 年 10 月 1 日
Model-based Meta-analysis for Quantifying Paclitaxel Dose Response in Cancer Patients
Model-based meta-analysis of dose response is a sophisticated method to guide dose and regimen selection.…
webdev2014 年 5 月 21 日
A Model-based Meta-analysis to Compare Efficacy and Tolerability of Tramadol and Tapentadol for the Treatment of Chronic Non-malignant Pain
Pain is a major symptom in many medical conditions which can be relieved thanks to…
webdev2014 年 2 月 13 日
