Augmented Definitive Screening Design Provides Efficient Phase 1 Selection of CAR T-cell and Lymphodepletion Regimen Poster 增强型确定性筛选设计为 CAR-T 细胞和淋巴清除疗法的 1 期筛选提供了高效率 Danielle Pillsbury2024 年 11 月 22 日
Oncology MIDD Simulator, A User-Friendly Application for Overall Survival Forecasting in Early Oncology Trials Poster 肿瘤学 MIDD 模拟器 — 用于早期肿瘤学试验总生存期预测的用户友好型应用程序 Danielle Pillsbury2024 年 11 月 22 日
Quantitative Systems Pharmacology model for combined targeting of BAFF and CD40 pathways in systemic lupus erythematosus Poster 系统性红斑狼疮中联合靶向 BAFF 和 CD40 通路的定量系统药理学模型 Danielle Pillsbury2024 年 11 月 22 日
Population pharmacokinetic modeling of niraparib to assess different absorption models Poster 尼拉帕利(Niraparib)群体药代动力学建模以评估不同吸收模型 Danielle Pillsbury2024 年 11 月 22 日
Recent applications of pharmacometrics and systems pharmacology approaches to improve and optimize drug therapy for pregnant and lactating women Publication 定量药理学和系统药理学方法在改善和优化孕妇和哺乳期妇女药物治疗方面的最新应用 The article "Recent Applications of Pharmacometrics and Systems Pharmacology Approaches to Improve and Optimize Drug…Danielle Pillsbury2024 年 11 月 18 日
PBPK Modeling to Support Bioequivalence & Generic Product Approvals Blog 支持生物等效性和仿制药审批的 PBPK 建模 Physiologically-based pharmacokinetic modeling can be used to support bioequivalence (BE) assessment of complex and locally…Jim Gallagher2024 年 11 月 12 日
A Sequential Population Pharmacokinetic Model of Zilovertamab Vedotin in Patients with Hematologic Malignancies Extrapolated to the Pediatric Population Publication 齐洛韦坦单抗维多汀(Zilovertamab Vedotin)在血液恶性肿瘤患者中的序贯群体药代动力学模型推断至儿童群体 Danielle Pillsbury2024 年 11 月 7 日
Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a recombinant human monoclonal antibody Publication 通过对重组人单克隆抗体进行靶向药物处置建模和模拟,为妊娠剂量提供依据 The article titled "Informing pregnancy dose via target-mediated drug disposition modeling and simulations for a…Danielle Pillsbury2024 年 11 月 4 日
Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women Publication Using PBPK modeling to supplement clinical data and support the safe and effective use of dolutegravir in pregnant and lactating women The article titled "Using PBPK modeling to supplement clinical data and support the safe and…Danielle Pillsbury2024 年 10 月 30 日
A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk Publication A close examination of BCRP’s role in lactation and methods for predicting drug distribution into milk The article, authored by Caroline Sychterz, Hong Shen, Yueping Zhang, Michael Sinz, Amin Rostami-Hodjegan, Brian…Danielle Pillsbury2024 年 9 月 18 日