Population Pharmacokinetic Analysis of Thrombomodulin Alfa to Support Dosing Rationale in Patients with Renal Impairment
Thrombomodulin alfa is a soluble recombinant human thrombomodulin that was reported to enhance the reversal…
webdev2015 年 5 月 1 日
Month 2 Culture Status and Treatment Duration as Predictors of Recurrence in Pulmonary Tuberculosis: Model Validation and Update
New regimens capable of shortening tuberculosis treatment without increasing the risk of recurrence are urgently…
webdev2015 年 4 月 29 日
Effect of Age and Sex on the Pharmacokinetics and Safety of Avibactam in Healthy Volunteers
Avibactam is a novel non-β-lactam β-lactamase inhibitor currently being assessed in combination with ceftazidime, ceftaroline…
webdev2015 年 4 月 1 日
Safety and Pharmacokinetics of Single and Multiple Ascending Doses of Avibactam Alone and in Combination with Ceftazidime in Healthy Male Volunteers: Results of Two Randomized, Placebo-controlled Studies
Avibactam is a novel non-β-lactam β-lactamase inhibitor effective against Ambler class A, C and some…
webdev2015 年 3 月 27 日
Chemotherapy of Second Stage Human African Trypanosomiasis: Comparison Between the Parenteral Diamidine DB829 and Its Oral Prodrug DB868 in Vervet Monkeys
Human African trypanosomiasis (HAT, sleeping sickness) ranks among the most neglected tropical diseases based on…
webdev2015 年 2 月 15 日
Population Pharmacokinetics of Ceftolozane/Tazobactam in Healthy Volunteers, Subjects with Varying Degrees of Renal Function and Patients with Bacterial Infections
Ceftolozane/tazobactam is a novel antipseudomonal cephalosporin and a β-lactamase inhibitor in clinical development for treatment…
webdev2015 年 2 月 1 日
Pharmacokinetics of Injectable, Long-acting Nevirapine for HIV Prophylaxis in Breastfeeding Infants
Mother-to-child transmission (MTCT) of HIV-1 remains a global health problem. The World Health Organization (WHO…
webdev2015 年 1 月 1 日
Pharmacokinetics of Vancomycin in Critically Ill Patients in Thailand
The pharmacokinetics and pharmacodynamics of drugs in critically ill patients are difficult to predict due…
webdev2014 年 12 月 1 日
