Absolute Abundance and Function of Intestinal Drug Transporters: A Prerequisite for Fully Mechanistic In Vitro-In Vivo Extrapolation of Oral Drug Absorption Publication Absolute Abundance and Function of Intestinal Drug Transporters: A Prerequisite for Fully Mechanistic In Vitro-In Vivo Extrapolation of Oral Drug Absorption The use of whole body physiological-based pharmacokinetic (PBPK) models linked with in vitro-in vivo extrapolation…webdev2013 年 1 月 1 日
Applications of Physiologically-based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review Publication Applications of Physiologically-based Pharmacokinetic (PBPK) Modeling and Simulation During Regulatory Review Physiologically based pharmacokinetic (PBPK) modeling and simulation is a tool that can help predict the…webdev2011 年 2 月 1 日
Population-based Mechanistic Prediction of Oral Drug Absorption Publication Population-based Mechanistic Prediction of Oral Drug Absorption The bioavailability of drugs from oral formulations is influenced by many physiological factors including gastrointestinal…webdev2009 年 6 月 1 日
Model-based Development of Gemcabene, a New Lipid-altering Agent Publication Model-based Development of Gemcabene, a New Lipid-altering Agent The purpose of this study was to evaluate the value of model-based, quantitative decision making…webdev2005 年 10 月 7 日