Clinical Pharmacology Archives

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确保抗体-药物偶联物开发最大概率获得成功的关键考虑事项

Antibody drug conjugates (ADC) are a unique way to obliterate tumor cells and represent an…

Rajesh Krishna2021 年 7 月 8 日

Blog

成功开发寡核苷酸疗法的 8 条小贴士

By Eva Gil Berglund and Nathalie H Gosselin Oligonucleotide therapeutics are a validated class of…

Eva Gil Berglund and Nathalie H Gosselin2021 年 2 月 1 日

White Paper

“Where do I start?”: Strategies for selecting the first dose for human clinical trials

This guide to dose selection for first-in-human studies explains the conceptual framework, methods, and tools…

Jim Gallagher2020 年 12 月 22 日

Blog

Clinical Pharmacology Gap Analysis: Lessons Learned

Clinical pharmacology gap analysis is a tool for outlining your drug program’s needs, prioritizing these…

Julie Bullock, PharmD2018 年 8 月 10 日

Publication

Metformin Treatment of Type 2 Diabetes Mellitus in Pregnancy: Update on Safety and Efficacy

webdev2018 年 4 月 25 日

Blog

Using M&S to Evaluate Oncology Drug Dosing

There are numerous challenges in developing oncology drugs: (1) they are often very toxic which…

Maria Saluta2018 年 4 月 13 日

Blog

Using a Pharmacology to Payer Framework to Support Product Development

Modeling and simulation (M&S) of complex systems has primarily advanced vertically in differing scientific domains…

C. Kirkpatrick, C. Rayner2018 年 3 月 16 日

Publication

Cost-utility Analysis of Antiviral Use Under Pandemic Influenza Using a Novel Approach—Linking Pharmacology, Epidemiology and Heath Economics

webdev2018 年 3 月 1 日

Blog

勘测全球范围监管申请建模与模拟的现状

Analogous to how a geologist surveys the “lay of the land” to determine if oil…

Maria Saluta2018 年 2 月 16 日

Publication

Clinical Pharmacology Tools and Evaluations to Facilitate Comprehensive Dose Finding in Oncology: A Continuous Risk-Benefit Approach

webdev2017 年 9 月 15 日

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确保抗体-药物偶联物开发最大概率获得成功的关键考虑事项

成功开发寡核苷酸疗法的 8 条小贴士

“Where do I start?”: Strategies for selecting the first dose for human clinical trials

Clinical Pharmacology Gap Analysis: Lessons Learned

Metformin Treatment of Type 2 Diabetes Mellitus in Pregnancy: Update on Safety and Efficacy

Using M&S to Evaluate Oncology Drug Dosing

Using a Pharmacology to Payer Framework to Support Product Development

Cost-utility Analysis of Antiviral Use Under Pandemic Influenza Using a Novel Approach—Linking Pharmacology, Epidemiology and Heath Economics

勘测全球范围监管申请建模与模拟的现状

Clinical Pharmacology Tools and Evaluations to Facilitate Comprehensive Dose Finding in Oncology: A Continuous Risk-Benefit Approach

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