Certara Pharmacometrics Services use quantitative methods and various modeling approaches to quantify the interactions between drugs and patients, helping to characterize efficacy, safety, and biomarker responses. The specific applications guide key topics such as dose selection, optimization for patient factors, and study design decisions, ensuring to obtain a drug’s optimal benefit-risk profile throughout development.
Pharmacometrics Services
Optimize drug development and regulatory decisions
建模和模拟服务
Learn more about our pharmacometrics services
Advancing drug development with Certara Pharmacometrics Services
Data-driven decision support
Leverage quantitative frameworks to drive safer, more efficient drug development.
Leverage quantitative frameworks to drive safer, more efficient drug development.
Design smart trials, improving the likelihood of success.
Regulatory-ready analysis
Deliver high quality, compliant PK and PK/PD analyses for submission.
Combining world class pharmacometricians and technology for superior drug development insights
The Certara Pharmacometrics team designs and implements MIDD strategies for all types of drug development programs, regardless of therapeutic area, drug modality, and development phase.
Largest network of global experts
With over 120+ PhD, PharmD, and MD consultants, Certara provides unmatched expertise across therapeutic areas and development phases.
Proven Regulatory Succes
Over 90% of novel drugs approved by the US FDA have used Certara’s software and services.
High-quality datasets
Certara data programmers ensure datasets are ready for fit-for-purpose PK and PK/PD modeling.
Unmatched expertise at every stage of drug development
Meet our pharmacometrics experts
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专家
Rik de Greef
Senior Vice President, Global Quantitative Sciences Services, Certara Drug Development Solutions
Rik de Greef 是 Certara 公司全球定量科学服务的高级副总裁。Rik 曾在荷兰莱顿大学接受 PK-PD 科学家培训。多年来，Rik 在 Organon 及其后继公司 Schering-Plough 和 Merck/MSD 担任了重要职务。
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专家
Stephen Duffull
Senior Scientific Advisor, Quantitative Science Services (New Zealand)
Stephen provides advanced pharmacometrics guidance for complex drug development challenges.
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专家
Matt Zierhut, PhD MBA
Vice President, MBMA Capability Lead, Certara Drug Development Solutions
Matt advances the integration of published clinical outcomes data into development decisions and commercial and regulatory strategy via model-based meta-analysis (MBMA). Matt 与临床开发团队密切合作，确保在做出最关键决策的时候，能利用 MBMA 发挥最佳影响力。
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专家
Adekemi Taylor, PhD
VP Regional Lead USA, Division 1, Quantitative Science Services
Adekemi specializes in in pharmacometric strategy and analyses (including population PK, PK/PD, efficacy and safety exposure-response, and concentration-QTc modeling) to support regulatory filings, study design, and general drug development.
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专家
Amy Cheung, PhD
Certara 药物研发解决方案副总裁
Dr. Cheung 在阿斯利康制药公司拥有十多年的工作经验，曾担任高级定量药理学家和阿斯利康儿科工作组项目经理。She obtained her Ph.D. from the University of Manchester.
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专家
Paul Matthias Diderichsen
Senior Vice President, Quantitative Science Services (Europe/Africa)
Paul excels in pharmacometrics modeling, project leadership, and client relations, focusing on decision support and regulatory filings across various therapeutic areas.
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专家
JF Marier, PhD
Sr. Vice President, Integrated Drug Development
JF 在进行 PK、PK/PD 和暴露水平-反应分析以支持各种治疗领域中的给药依据方面，拥有 25 年经验。专长包括肿瘤、罕见病和儿科人群。
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专家
Mirjam Trame
VP, Certara Drug Development Solutions, Head of Pharmacometrics USA – Division II
Mirjam 是一名药物代谢动力学顾问，在 Certara 公司担任美国药代动力学 II 部门总监。她拥有涵盖多种模式的专业知识，包括复杂生物制剂，并专注于细胞和基因疗法领域。
预约咨询相关资源
查看全部Partner with Certara to leverage the world’s most experienced pharmacometrics team. Our experts are dedicated to delivering innovative, regulatory-compliant solutions that optimize drug development outcomes.
Access a team of 120+ pharmacometricians with proven expertise.
Utilize high-quality datasets and advanced quantitative methods.
Maximize success with data-driven decisions at every stage.
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常见问题解答
What is pharmacometrics?
Pharmacometrics uses mathematical modeling to quantify drug-patient interactions, supporting regulatory decisions and optimizing drug development.
Certara 如何支持监管申请？
Certara provides regulatory-compliant PK/PD analyses and modeling to ensure successful submission packages.
What phases of drug development does Certara support?
Certara supports all phases, including preclinical, early clinical, and late clinical development.
