Certara’s Drug Interaction Consulting Services empower pharmaceutical researchers and regulatory scientists to decode complex drug interactions. By leveraging the scientist-curated DIDB and our team’s extensive expertise, we deliver actionable insights to improve clinical decision-making and ensure patient safety. Our services include literature and NDA reviews, mechanistic assessments, and evaluations of PK variability to guide study designs and optimize therapeutic outcomes.
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Get more value out of your Drug Interaction Database (DIDB) license
Learn more about drug interaction solutions consulting services
Draw on drug interaction expertise to improve clinical decision making
Shorter DIDB learning curve
Learn from the in-house team with expertise in drug metabolism, transport, pharmacokinetics, drug interactions and clinical pharmacology responsible for curating and maintaining DIDB
Decode drug interactions
Certara consultants are available to help pharmaceutical researchers and regulatory scientists meet their project goals, improve clinical decision making and ultimately, enhance patient safety.
More efficient problem solving
Intimate knowledge of the DIDB platform helps end users with highly specific and detailed database searches and outputs.
Examples of drug interaction solutions consulting services include, but are not limited to
对风险进行详细的机制评估
Assess risk of drug-drug interactions between a drug candidate and known substrates and perpetrators or enzymes and transporters (including food and herbal products).
Review of literature and NDAs
Use this information to guide DDI study design, for example, in vitro evaluations, clinical studies and more.
PK 变异性评估
Evaluate PK variability of common drug substrates to guide calculation of the number of subjects.
肝肾功能损伤的影响
Optimize pricing and access strategies.
酶和转运体基因多态性的影响
Understand the impact of gene polymorphism of enzymes and transporters on drug exposure.
深入了解复杂的 DDI 机制
以最新的科学和机制知识为基础，深入探讨 DDI 的复杂机制。
Meet our drug interactions consulting services leaders
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专家
Isabelle Ragueneau-Majlessi, MD, MS
Distinguished Scientist, Drug Interaction Solutions
Dr. Ragueneau is a co-founder of the Drug Interaction Database (DIDB) and leads the Drug Interaction Solutions program.
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专家
Jingjing Yu, MD, PhD
Director, Drug Interaction Solutions
Dr. Yu brings over 15 years of experience in drug metabolism and clinical pharmacology, and brings a unique expertise in the field of drug interactions gained through her work in both academia and industry.
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Partner with Certara’s drug interaction experts to elevate your clinical decision-making processes. Our team is dedicated to providing innovative solutions and unparalleled support for your drug development needs.
Access in-depth literature and NDA reviews for regulatory submissions.
Leverage comprehensive mechanistic and PK variability evaluations.
Ensure patient safety with tailored insights into drug interactions.
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常见问题解答
What is the DIDB?
Certara’s Drug Interaction Database (DIDB) is the industry’s largest expertly curated database to assess drug interactions and safety.
How can Certara assist with NDA reviews?
Our consultants review NDAs to guide study designs and address regulatory requirements.
What services do you offer in drug interaction consulting?
We offer literature reviews, mechanistic risk assessments, and PK variability evaluations.
