What is WinNonlin?
A reader suggested that I write a similar post about WinNonlin. Great idea! Thank you!…
Nathan Teuscher2011 年 3 月 16 日
个体 PK 和群体 PK 有什么区别？
药代动力学分析通常分为两个领域...... "PK "和 "群体 PK"。Sometimes the…
Nathan Teuscher2011 年 3 月 14 日
Blood or Plasma? Which Should You Assay for Drug Concentration?
Explore blood vs. plasma drug concentration assays. Learn their differences, relationships, and impact on accurate…
Nathan Teuscher2011 年 2 月 19 日
Why Should You Evaluate Dose Proportionality?
Dose proportionality is a common phrase used pharmacokinetics. Early in the pre-clinical development process, we…
Nathan Teuscher2011 年 2 月 17 日
What is the Difference Between PK and TK?
Explore the key differences between pharmacokinetics (PK) and toxicokinetics (TK), their roles in drug development,…
Nathan Teuscher2011 年 2 月 15 日
Why are PK Parameters Lognormally Distributed?
The statistical analysis of pharmacokinetic parameters is often overlooked and not always well understood. The…
Nathan Teuscher2011 年 2 月 10 日
What are Direct and Indirect Pharmacodynamic Models?
When constructing pharmacodynamic (PD) models, you will often encounter the adjectives “direct” and “indirect” describing…
Nathan Teuscher2011 年 2 月 8 日
What is Modeling and Simulation?
I am currently attending a short conference on modeling and simulation in pediatric clinical pharmacology,…
Nathan Teuscher2011 年 2 月 1 日
Relationship Between AUC and Volume of Distribution
A few days ago on the pharmacokinetics listserve PharmPK, the following question appeared: I’m having…
Nathan Teuscher2011 年 1 月 26 日
Where Did the 80-125% Bioequivalence Criteria Come From?
Most people involved in clinical pharmacokinetics are familiar with the 80-125% criterion. This criterion is…
Nathan Teuscher2011 年 1 月 24 日
