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预测 CYP3A4 代谢药物的儿科药代动力学:基于生理的药代动力学模型中两种肝脏本构的性能比较

The rapid growth in the use of pediatric physiologically based pharmacokinetic (PBPK) models, particularly for regulatory applications, has focused emphasis on model verification and ensuring system parameters are robust, including how …

Author(s): Marc Codaccioni PhD, Rosalind L. Southall MSc, Jean Dinh PharmD, PhD, Trevor N. Johnson PhD

Year: 2024 年 5 月 2 日

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